COMPARISON OF RACECADOTRIL WITH ORAL REHYDRATION SOLUTION IN ACUTE WATERY DIARRHEA UNDER 5 YEARS OF AGE

BACKGROUND: A significant share (18%) of paediatric mortality is caused by diarrheal diseases. Children under the age five are most susceptible to viral diarrhoea. In cases acute watery diarrhoea, racecadotril, an anti-secretory medication, can limit fluid and electrolyte loss from intestine without compromising intestinal motility.
 OBJECTIVE: To compare number loose stools within first 48 hours admission between children treated with Racecadotril, as well mean recovery time in both groups, order determine efficacy Racecadotril treating diarrhoea aged 6 months 5 years.
 METHOD: It was a Randomized Controlled Trial that ran October 2020 March 2021 at Paediatrics Department LGH/PGMI/AMC Lahore. Patients were divided into two equal groups random using computer-generated table. (1.5 mg/kg body weight, orally three times per day for days or until ceases, whichever happens first) given 100 patients group coupled Low Osmolality ORS, while ORS B. For testing blood haemoglobin, urea creatinine, sugar, serum electrolytes, stool (pH, microscopic inspection, culture, sensitivity), samples sent hospital pathology lab. As operational definition, documented.
 RESULTS: our study, 37.88 (racecadotril plus low osmolality ORS) 47.40 B (low ORS), demonstrating substantial reduction 20.08 percent (p value = 0.0026). The 48-hour frequency 11.34 episodes + 14.98 group, statistically decrease 24.29 0.025). Faster (20.08 percent) 20.52 consumption, which comparable earlier trials on conducted diarrhoea.
 CONCLUSION: managing who have we came conclusion there difference when Oral Rehydration Solution (ORS) used combination